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Indeed, because of their presence in almost every tissue and organ in the body, it is not surprising that fibroblasts are now implicated in multiple and diverse conditions ranging from well-known diseases like cancer, rheumatoid arthritis or fibrosis, to poorly understood ones like fibromyalgia, chronic pain or thyroid eye disease, as we will discuss below ( Figure 1 )
Long-term continuous treatment offers several advantages
Retatrutide did show a slight increase in heart rate in some patients (something also seen with other GLP-1 drugs), but this tended to level off over time
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& Eijsvogels, T
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