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Diminished parasympathetic modulation of the heart resulting in increased HR was also observed in response to intracerebroventricular infusion of exendin-4 in mice [36]

Dulaglutide (Trulicity) begins at 0.75 mg once weekly, with potential increases to 1.5 mg, 3 mg, or a maximum of 4.5 mg weekly based on glycemic response

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