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Store reconstituted vials refrigerated at 2-8 degrees Celsius, and most sources report stability for 30-60 days once reconstituted, provided you avoid repeated freeze-thaw cycles

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The topical route is the format with the strongest human clinical trial evidence for skin outcomes, from the landmark 1998 Abdulghani study that outperformed both vitamin C and tretinoin to the Finkley skin-thickness data

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