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However, dual GIP and GLP-1 receptor agonists showed better efficacy with regard to glucose control and weight loss with an acceptable safety and tolerability profile [3]
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GLP-1 EFFECT ON FATTY ACID OXIDATION IN LIVER AMP-activated protein kinase (AMPK) and silent mating type information regulation 2 homolog (sirtuin, SIRT) 1 are metabolic sensors regulating energy homeostasis and various intracellular systems
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