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The fact is that no over-the-counter supplement has been proven to significantly or consistently increase GLP-1 levels in humans
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Additive effects on weight loss were similarly demonstrated in the Efficacy and Safety of Semaglutide Once-weekly Versus Placebo as add-on to SGLT-2i in Subjects With Type 2 Diabetes Mellitus (SUSTAIN-9) and Dulaglutide as add-on therapy to SGLT2 inhibitors in patients with inadequately controlled type 2 diabetes (AWARD-10) trials [103,104]
It does not directly address dietary supplements containing BPC-157
Patients should also be aware that delayed gastric emptying may affect the absorption of certain oral medications, particularly those with a narrow therapeutic index
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