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These data reveal that cagrilintide has an amylin-like binding mode but, compared to other peptides, induces distinct conformational dynamics at calcitonin-family receptors that could contribute to its clinical efficacy

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In diet-induced obesity (DIO) mouse models, 5-Amino-1MQ administered intraperitoneally produced a 7% reduction in body weight over 11 days compared to vehicle-treated controls, despite no change in food intake

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State Reconstituted (liquid) Storage 35.6-46.4 F (2-8 C) refrigerated Notes Use within 14-28 days

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