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& Spiegelman, B
Currently, only Novo Nordisk is authorized to manufacture semaglutide and generic semaglutide is not yet available in the United States
For decades, research has primarily focused on the amyloid hypothesis, which posits that the accumulation of amyloid-beta protein in the brain is the principal cause of the disease (Maccioni Ricardo B et al., 2020)
This is most likely due to the Wow factor
Head-to-head comparative trials examining inflammatory outcomes as primary endpoints are limited, and most evidence comes from individual studies or post-hoc analyses of cardiovascular outcome trials
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