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Unlike some other compounds in its class, ipamorelin avoids triggering cortisol and prolactin spikes, which enhances its overall tolerability
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Conversely, Gotthard and colleagues showed that in a model of murine lymphoma (26), STAT-5-deficient NK cells expressed elevated levels of VEGF and were able to induce endothelial cell sprouting ex vivo
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No significant endocrine adverse events were reported, consistent with its selective pharmacological profile
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