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Dupr y Viraben 6 agrupan bajo la denominacin de enfermedad de Laugier un conjunto de entidades con diversas denominaciones segn la localizacin topogrfica: mcula melantica labial, pigmentacin melnica adquirida del labio inferior, mcula melantica oral, lentigo labial solitario, lentiginosis genital, lentiginosis del pene y de vulva, lentigo atpico del pene y melanosis del pene

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In the CUPRAC method, the CUPRAC reagent Cu(Nc) 2 2+ was added to stop the enzymatic reaction after a sufficient period of incubation