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4-Pantetheinylation of formyltetrahydrofolate dehydrogenase (FDH) The figure shows two reactions involving FDH: Panel A: Holo-FDH (the biologically active FDH) catalyzes the conversion of 10-formyltetrahydrofolate into tetrahydrofolate using water and NADP + , releasing CO 2 , NADPH, and a proton (H + )
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Cross-linking is essential for the stabilization and mechanical support of collagen networks within native cartilage
[52] Gonzalez F, Considine RV, Abdelhadi OA, Acton AJ
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