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In neonatal models of hypoxicischemic injury, altered TJ protein levels have been detected in CSF and plasma, suggesting their potential as biomarkers for assessing BBB function and providing insight into early brain injury [285]
Meanwhile, phenothiazine-based derivatives compound 51 , although it has shown neuroprotective effects in IS animal models, still has high hERG inhibitory activity (Yang et al., 2021
PubMed Vukojevic J, Siroglavic M, Kasun M, et al
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