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A 2018 review in the International Journal of Molecular Sciences analyzed available gene expression data and found that GHK-Cu at clinically relevant concentrations affected the expression of approximately 31.2% of human genes [2]
The STING agonist 8803 induced direct cytotoxicity of ex vivo resected meningiomas, independent of CD45+ populations, in a process that depended in part on programmed necrotic cell death pathways (necroptosis, pyroptosis, ferroptosis) and reactive oxygen species production
10.1016/j.stem.2011.11.019 86 SalvagnoM.CoppaliniG.TacconeF
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It also reduced the accumulation of ROS, MDA, and 4-HNE, while enhancing GSH and NADPH expression and the NADP/NADPH ratio
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