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Low methionine levels can affect the production of A-adenosylmethionine (SAMe), a major methyl donor for the central nervous system and an essential nutrient required for the production of neurotransmitters

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The table below highlights the variables that most often determine whether a project gives a useful, interpretable product instead of a difficult polar mixture

Beyond the Basics: Advanced Considerations for Researchers For most protocols, the steps outlined above are all you'll need