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Depression damages these processes

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In a controlled study by Samsom and colleagues, healthy subjects given pramlintide showed gastric-emptying half-times that lengthened from about 112 minutes on placebo to roughly 169 minutes at 30 g and 177 minutes at 60 g a delay of more than an hour at the higher dose

The delayed gastric emptying also enhances the incretin response, creating a complementary effect with GLP-1 based therapies

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