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For instance, depletion of mGSH results in Trx2 oxidation (Zhang et al., 2007), while hypercholesterolemic pigs with selective depletion of mGSH in heart mitochondria, exhibit decreased levels of the mitochondria-specific antioxidant enzymes such as SOD2, Trx2, and Prx3 (McCommis et al., 2011)
Acetyl-L-carnitine attenuates arsenic-induced oxidative stress and hippocampal mitochondrial dysfunction
L-carnitine can also have a slightly fishy smell, which is both normal and natural
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