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GLP-1R and GIPR activation in hypothalamus and area postrema investigated for modulation of appetite-regulating neuroendocrine pathways

Activation of GLP-1R also enhances the levels of anti-inflammatory cytokines like IL-4 and IL-10, along with increasing the expression of the neuroprotective factor -endorphin in microglia [112]

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L-Carnitine has been the subject of much scientific research which has confirmed the benefits of supplementation