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It also slightly elevates the possibility of cancer with prolonged high doses
Also, high mobility group box 1 (HMGB1) is released upon injury, which forms an HMGB1-CXCL12 complex to shift CXCR4 + MuSCs to the G Alert state [95]
A key difference between the two drugs is that Zepbound is a dual receptor agonist that works on both GLP-1 and gastric inhibitory polypeptide (GIP)
GIP, glucose-dependent insulinotropic polypeptide, improves insulin sensitivity and plays a direct role in lipid metabolism
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