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They can be used intermittently and are a popular rejuvenation therapy for exhaustion, burn out, migraines and of course post-party nausea

Maintenance dose is not necessarily permanent

However, the peptide characteristics that enable absorption through the gastric mucosa, including its stability in acidic environments and resistance to enzymatic degradation, suggest it should maintain activity when absorbed through nasal mucosa as well

Specifically, it upregulates genes involved in collagen synthesis (Types I, III, and V), decorin production (which regulates collagen fibril assembly), integrin and glycosaminoglycan synthesis, DNA repair enzymes, antioxidant defense systems (superoxide dismutase, glutathione), and stem cell markers

Sheth, V