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Although this did not reach statistical significance, the magnitude and direction of the effect suggest that a clinically meaningful benefit cannot be excluded, highlighting the need for larger, adequately powered multicenter randomized trials

This gradual increase is intentional and designed to help the body adjust more comfortably

It works quietly in the background to support cellular metabolism and reduce oxidative stress

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Oxidative Stress and Autoimmune Thyroid Disease Thyroid follicular cells are among the most metabolically active tissues in the human body, generating significant quantities of hydrogen peroxide (H2O2) during thyroxine (T4) and triiodothyronine (T3) synthesis