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While the liver plays a significant role in systemic glutathione metabolism, the central nervous system (CNS) maintains its own tightly regulated GSH pool, independent of peripheral control (3-4)
pyroglutamic (5-oxoproline) acidosis pyroglutamic (5-oxoproline) acidosis pathophysiology pathogenesis of pyroglutamic acidosis The primary driver may be cysteine deficiency : Cysteine deficiency causes glutamylcysteine to be shunted into 5-oxoproline
10.3389/fncel.2018.00313 111
In this sense, glutathione is less a single antioxidant than an antioxidant system manager
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