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In SM, hyperpigmentation can vary in severity and location, but its distinctive characteristics make it easily identifiable
Brown TyrBm crystals indicate on substrate oxidation as was previously shown by Sendovski et al
However, with only four cases and single-center data, this limits the generalizability of our findings and precludes any definitive conclusions regarding causality
In 2002, one study (2) showed that supplementing with 200ug selenium for 3 months decreased antibodies (anti-TPO) from 900 to 600 IU/ml
10.3201/eid2608.201413 26 El-AshmawyN
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