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Its impossible to know if this is due to reduced absorption or just the typical pill failure rate of 9% annually with typical use, but the theoretical risk is concerning enough that many doctors recommend alternative contraception

All recommendations by the ADA regarding GLP-1 RAs have been assigned an A rating, which is the associations highest rating of evidence

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2026 Trends: While exact 2026 national hospital figures are still being tracked, regional research from the University of New Mexico shows that up to 44% of reported GLP-1 exposure cases in 2026 are severe enough to require an immediate emergency room visit.

8 Because ascorbate is a carbohydrate, it is biochemically plausible that vitamin C induces damage in the lens in vivo