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A higher risk of deficiency is present in patients with malabsorptive syndrome and/or unusually low sun exposure, those who have undergone gastric bypass surgery, or those on prolonged glucocorticoid use (which alters intestinal absorption) (46)

Compared with baseline, the results showed a significant increase in collagen fiber network (fiber cross-linking and fiber length) along with a significant increase in epidermal hyaluronic acid levels

Patients commonly report deeper, more restorative sleep within the first two to four weeks