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Molecular Medicine, 2012
Even at very low, nanomolar amounts it switches on the skin's repair programs prompting fibroblasts (the cells that build the skin's scaffolding) to lay down fresh collagen and support molecules, while dialling down the inflammation and oxidative stress that age tissue.[2][3] There's also the gene-level angle
10.1016/j.tplants.2018.03.016 163 VeluchamyS.PantheeD
Some particularly cautious protocols extend initial phases to 4-6 weeks, especially in patients with medical complexity or those extremely concerned about side effects
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