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However, despite the clinical evidence that serum E2 levels are inversely correlated with psoriasis severity, and replacement therapy with low-dose E2 administration in may improve psoriasis, tamoxifen, an antiestrogen agent, results in the remission of psoriasis, thus suggesting that estrogens might exert both pro-inflammatory and anti-inflammatory effects in psoriasis [124]
Follow-up The symptoms of anaemia usually start to improve within a few weeks once treatment has begun
Inflammatory cell infiltration follows tissue injury, initially serving protective functions but potentially causing secondary damage if prolonged or excessive
They usually resemble in appearance the classical rash of a viral infection (many pink-to-red macules usually first appearing on the trunk and then spreading to the limbs and neck
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