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Studies have demonstrated GLP-1 injections effectiveness in weight loss, with a significant percentage of participants achieving substantial weight reduction when combined with lifestyle changes
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GABA released by the NPY/AgRP neurons is very important to the control of food intake probably via inhibiting the anorectic effects of the POMC neurons
The SELECT trial, which evaluated semaglutide 2.4 mg against placebo for cardiovascular outcomes in patients with overweight and obesity without type 2 diabetes, showed significant decreases in total cholesterol, LDL-C, and triglycerides and an increase in HDL-C at 39.8 months [48]
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