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[69] [70] Compliance with the updated labeling regulations was required by 1 January 2020 for manufacturers with US$10 million or more in annual food sales, and by 1 January 2021 for manufacturers with lower volume food sales

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American Family Physician, 96(6), 384-388

The Journal of Obstetrics and Gynaecology of the British Commonwealth

Follow institutional protocols or product labeling for guidance on maximum duration of use after opening (typically ranging from hours to days depending on clinical setting and protocol)