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Using a long-term HFD-fed mouse model of NAFLD, we demonstrated in this study that NAFLD development occurs concomitantly with dysregulated hepatic glutathione homeostasis characterized by decreased GSH and increased GSSG, and increased TNF protein levels in both the circulation and the liver

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In addition, about 10% of the samples from each study group were randomly selected to perform direct sequencing of the PCR products of each polymorphism

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To overcome the "absorption gap," advanced delivery methods are required