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Small peptides like GLP-1 and GLP-2 are rapidly cleared in vivo , leading to low circulating levels
Liraglutide and semaglutide are both safe GLP-1 medications but Liraglutide is generally easier on the stomach, while semaglutide is more potent and slightly more likely to cause side effects
At present, increasing evidence has shown that compounds derived from natural medicines exert a variety of beneficial effects, including antioxidant, anti-inflammatory, and anti-apoptosis effects [119,120,121]