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Hallmark pathological features include degeneration of DA neurons in the substantia nigra and the presence of Lewy bodies (LBs) within surviving neurons (Sulzer et al., 2017)
To improve DE differentiation, the researchers incorporated PI3K inhibitor LY294002 (Ly) or CDK4/6 inhibitor PD into the small-molecule cocktails
No safety data for any of the three peptides during pregnancy
Consulting with a knowledgeable healthcare provider familiar with peptide therapy ensures optimal treatment selection and monitoring
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