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Declining estrogen affects thermoregulation (hot flashes), mood regulation, and even melatonin receptor sensitivity

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At the highest doses, retatrutide seems to promise more significant weight loss than existing GLP-1s on the market but as dosage increases, so does the risk of side effects, mostly mild-to-moderate gastrointestinal issues, although one case of pancreatitis occurred in a patient on the 12mg dose during the phase II trial

But what most people dont realize is how inconsistent it can be depending on where it comes from and how its used

Refrigeration often extends shelf life even when not required