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The most frequently reported adverse effects of semaglutide are gastrointestinal in nature, reflecting the medication's mechanism of slowing gastric emptying and its effects on the gastrointestinal tract
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Data collected from a randomized, placebo-controlled, double-blind trial of liraglutide 3.0 mg, in which nausea was the most frequent adverse event, showed that greater weight loss was associated with transient nausea and vomiting in participants with obesity but without diabetes [50]
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