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Neurochem Res (2010) 35:15301537

To mitigate IGF-1 side effects such as joint pain, swelling, and nerve compression, bodybuilders can follow several strategies: use the lowest effective dose under medical supervision, rotate injection sites, maintain proper hydration, support joints with supplements like glucosamine or omega-3 fatty acids, and incorporate stretching and mobility exercises

Biomechanical studies using human motion segments have been shown that endplate fracture can already occur with an axial force (0.5 mm/sec) of 4.5 kN depending on the spinal alignment

Each treatment was done in triplicate and each experiment was done three times

This can happen due to certain health issues or diet