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not yet approved Tirzepatide : FDA-approved as Mounjaro (2022) for T2D and Zepbound (2023) for obesity Advantage : Tirzepatide Side Effect Profile# Retatrutide : GI side effects common
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In addition to the FDAs scrutiny of outsourcing facilities and compounders in the GLP-1 space, the FDA has expressed concerns over the use of unapproved GLP-1 drugs for weight loss, 2 including dosing concerns with compounded semaglutide and tirzepatide products, salt forms that should not be used to compound semaglutide, use of retatrutide in compounding, and adverse events related to compounded versions of semaglutide and tirzepatide, among others
Forward Look: Employers should prepare for integrating GLP1 coverage with screening, counseling, and monitoring
Electrolyte balance is important for heart rhythm and blood pressure
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