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Most people find these effects are strongest when starting the medication and tend to improve as their body adjusts

10.1007/s11250-021-02796-y 16 DowlathM

GLP-1 medications work by targeting key processes: Appetite suppression You feel full sooner and stay full longer Slower gastric emptying Food stays in your stomach longer, reducing hunger Blood sugar regulation Helps stabilize glucose levels Reduced cravings Especially for high-calorie foods Tirzepatide adds another layer by also acting on GIP receptors, which may enhance metabolic effects

"Pentadecapeptide BPC 157 and the intestine-the barrier." Journal of Physiology Paris

Children received a high-dose multistrain probiotic mixture (De Simone Formulation, 450 billion CFU/day)