glp 1 physiology informs the pharmacotherapy of obesity

glp 1 physiology informs the pharmacotherapy of obesity Revolutionizing treatment: emerging role GLP-1 receptor agonists and next-generation pharmacotherapies Mechanisms by which GLP-1 agonists

Name: glp 1 physiology informs the pharmacotherapy of obesity Revolutionizing treatment: emerging role GLP-1 receptor agonists and next-generation pharmacotherapies Mechanisms by which GLP-1 agonists
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doi: 10.1016/j.ygcen.2007.11.007 30 ZimmermannMB

IR/IGF-1 receptor hybrids and IR-A lead to an over-activation of the IGF pathway, causing an enhanced mitogenic signaling and cancer development (Malaguarnera et al., 2011)