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IGF-1 is the main anabolic mediator of growth hormone

4 min read Weight loss might be what gets the headlines, but for many people on GLP-1 medications like Ozempic, Wegovy, or Mounjaro, the most profound change isnt on the scale

however, indirect factors such as rapid weight loss, postural changes, gastrointestinal side effects, and rare complications like gallbladder disease or pancreatitis may contribute to back discomfort

Knottnerus SJG, Bleeker JC, Wst RCI, Ferdinandusse S, IJlst L, Wijburg FA, et al

9, 2025), available at: [3] FDA, FDAs Concerns with Unapproved GLP-1 Drugs Used for Weight Loss , (last visited: Sep