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found that GLP-1R activation reduced tumor growth and metastatic potential by inhibiting ERK1/2 and AKT phosphorylation, lowering MMP-2 and MMP-9 expression, and increasing E-cadherin
These findings establish CS-PS as a promising natural anti-fibrotic agent ( Figure 2 )
De Simone C et al
Other approaches Obesity is a widespread and heterogeneic disease that will require a variety of approaches, manufacturer Amgen has said, revealing that it is developing both oral and injectable approaches, comprising both incretin and non-incretin mechanisms
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