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doi:10.1016/j.archger.2022.104846 Rendina DN, Ryff CD, Coe CL
Health Canada review has historically trailed FDA approval by roughly 6 to 18 months for this drug class, which is where the late-2027-to-mid-2028 window comes from
Maquart F
Reference sheet on the Melanotan II and the melanocortin receptor family
However, any upward trend in weight exceeding 3-5 pounds should trigger immediate protocol review and potential dose adjustment
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