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10.1016/0006-291x(84)91253-1 83 NakamuraT.NishizawaT.HagiyaM.SekiT.ShimonishiM.SugimuraA.et al (1989)

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This established the mechanistic rationale for NNMT inhibition

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There are several limitations to the conclusions that can be drawn from the studies with PF and FF

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