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In addition to increases in insulin secretion and synthesis, GLP-1 suppresses Glc secretion, slows gastric emptying, reduces food intake, and promotes beta-cell proliferation

Visible changes in weight often become apparent within one to two months

Pricing information for oral GLP-1 weight loss medications has yet to be determined

Shortly after folic acid fortification was introduced, concerns were raised that higher intake might promote the progression of preneoplastic lesions in the colon (early cellular changes that could become cancer)

The adjustment is to use fat as the dietary lever you reduce when appetite is already suppressed, rather than forcing fat intake to hit macro targets