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Glutathione, the sole active ingredient, is a tripeptide composed of glutamine, cysteine, and glycine, and is recognized for its critical role in cellular defense against oxidative stress, as well as its involvement in numerous metabolic and detoxification pathways
NNMT (nicotinamide N-methyltransferase) is the enzyme 5-Amino-1MQ inhibits, and tissue expression varies significantly across organs: adipose tissue shows 812 higher NNMT activity than skeletal muscle, which is why subcutaneous injection near adipose depots produces localised effects rodent models couldn't predict
I have no hard evidence , just what Ive read on this forum for over 9 years
PloS ONE 9 , e97673 (2014)
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