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For patients with refractory disease, surgical intervention focuses on neural decompression and, when indicated, motion segment stabilization

The Phase 2 cohort lost 8.7% at 48 weeks

Functional heterogeneity of marginal zone B cells revealed by their ability to generate both early antibody-forming cells and germinal centers with hypermutation and memory in response to a T-dependent antigen

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Vial fill and identity are verified by independent third-party testing and documented on the lot's Certificate of Analysis