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Low-impact movement during stable periods When disease activity is low, lupus patients on tirzepatide should aim for regular low-impact exercise

It binds to both GIP and GLP-1 receptors, which are G-protein-coupled receptors expressed in pancreatic beta cells, the gastrointestinal tract, adipose tissue, and the central nervous system

Alternative approaches include supplementing with precursor nutrients such as N-acetylcysteine (NAC), which the body can use to synthesise glutathione naturally, though NAC is also not recommended for NAFLD in NICE guidance and should not be self-prescribed for liver disease

Long-term safety in humans is uncharacterised for either component, individually or together

However, Semaglutide GLP-1 injections are one possible option for people experiencing this