This works, but it's painfully slow, and adherence becomes the limiting factor
Nature 570 , 246251 (2019)
However, because they initially absorb through oral membranes, bypassing the stomach to go straight to the bloodstream, they shouldnt need as high of a dose.6 Research indicates a certain amount of difficulty absorbing peptides through regular digestion, so sublingual absorption could prove superior.7 The only problem is that sublingual delivery mechanisms for semaglutide haven't been tested to establish an effective dose outside of the compounding pharmacy industrys internal publications, which are more marketing materials than clinical research
Due to the different methods for measurement of GSH, GSSG and consecutive GSH/GSSG ratio applied for in vivo determination of cellular redox state, published reports show quite pronounced differences in concentrations
The liposomal form protects glutathione bonds from the degradation that can occur in digestion