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Wegovy 7.2 mg achieved 20.7% average weight loss in the STEP UP trial, while Mounjaro 15 mg achieved 20.2% in the SURMOUNT-5 trial

1 So, its unclear whether the results can be generalisable to the broader population

The next wave of obesity medicine may include stronger, more complex metabolic therapies

Retatrutide (also known by its lab name LY3437943) works by activating three gut hormone receptors at once: GLP-1, GIP, and glucagon

124 Hence, the nature of the mutation has relatively little predictive value with respect to the severity of the clinical course and the phenotypic expression of identical mutations can be strikingly different in patients