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Aminoglycosides, tetracyclines, and certain other antibiotics may alter gut microbiota composition, potentially affecting the small amount of vitamin B12 that is produced by colonic bacteria, though this is generally not clinically significant for patients receiving injectable B12 supplementation
At the same time, it fine-tunes which collagen-clearing enzymes are active, striking a balance between breaking down old tissue and building new tissue, while also calming inflammation
"The 'Skinny' on brown fat, obesity, and bone." American Journal of Biological Anthropology , November 2014, Fielding, Roger et al
Funding This work was supported by the Project of Health Department in Zhejiang Province (2019KY681), Huzhou Municipal Science and Tech Commission (2018GY20), Huzhou Municipal Science and Tech Commission (2018GYB16)