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Recent Preoperative Lumbar Epidural Steroid Injection Is an Independent Risk Factor for Incidental Durotomy During Lumbar Discectomy

This state may be secondary to a persisting stressor, such as a redox imbalance (251), persistent infection (201, 251), injury (201), insufficient nutrients (201), cold temperatures (201), or it could be due to a defect in the switch that turns off this protective state (251)

Additionally, B12 is involved in reducing homocysteine levels, an amino acid linked to higher stress and anxiety