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Lancet (2009) 374:160616

Users report fewer gastrointestinal (GI) side effects, lower costs, and more gradual weight or metabolic changes than with full-strength regimens

Effects of GLP-1RAs on oxidative stress and mitochondrial function In patients with diabetes, chronic hyperglycemia can lead to excessive production of ROS and consequent imbalance in redox status in brain tissues, which may play an important role in the pathogenesis of ischemic stroke [85]

This kind of misses the point

New Jersey: Comprehensive Evaluation Required New Jersey requires prescribers to: Conduct a complete physical exam and appropriate lab tests Assess for psychiatric conditions and ensure theyre treated or stable before starting weight-loss meds Provide or arrange nutritional counseling, exercise recommendations, and behavioral modification Document all of this in the medical record This is actually an area where psychiatric providers have an advantage youre already screening for and treating mental health conditions, which many PCPs skip