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Nearly half of members taking GLP-1s for weight loss discontinued use, compared to about one-third of members taking GLP-1s for diabetes
Excessive glutamate release can lead to overexcitation of neurons, leading to anxiety, depression, and other neurological conditions
Ledinek AH, Sajko MC, Rot U
Daily totals up to 900 mcg (300 mcg three times per day) have been used in community protocols, but tolerability and side-effect risk climb at the high end
The article says research indicates estrogen influences GLP-1 signaling at multiple levels, including appetite centers and insulin-producing beta cells
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